Peptide and Protein Interaction with Membrane Systems

Applications to Antimicrobial Therapy and Protein Drug Delivery

Nonfiction, Science & Nature, Science, Chemistry, Analytic, Biological Sciences, Biochemistry
Cover of the book Peptide and Protein Interaction with Membrane Systems by Sara Bobone, Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Sara Bobone ISBN: 9783319064345
Publisher: Springer International Publishing Publication: May 31, 2014
Imprint: Springer Language: English
Author: Sara Bobone
ISBN: 9783319064345
Publisher: Springer International Publishing
Publication: May 31, 2014
Imprint: Springer
Language: English

In her thesis, Sara Bobone outlines spectroscopic studies of antimicrobial peptides (AMPs) which are promising lead compounds for drugs used to fight multidrug resistant bacteria. Bobone shows that AMPs interact with liposomes and she clarifies the structure of pores formed by one of these molecules. These results help us to understand how AMPs are selective for bacterial membranes and how their activity can be finely tuned by modifying their sequence. Findings which solve several conundrums debated in the literature for years. In addition, Bobone uses liposomes as nanotemplates for the photopolymerization of hydrogels - exploiting the self- assembly properties of phospholipids. Bobone was able to trap an enzyme using nanometeric particles, while still allowing its activity by the diffusion of substrates and products through the network of the polymer. The innovative nano devices described in this thesis could solve many of the hurdles still hampering the therapeutic application of protein-based drugs.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

In her thesis, Sara Bobone outlines spectroscopic studies of antimicrobial peptides (AMPs) which are promising lead compounds for drugs used to fight multidrug resistant bacteria. Bobone shows that AMPs interact with liposomes and she clarifies the structure of pores formed by one of these molecules. These results help us to understand how AMPs are selective for bacterial membranes and how their activity can be finely tuned by modifying their sequence. Findings which solve several conundrums debated in the literature for years. In addition, Bobone uses liposomes as nanotemplates for the photopolymerization of hydrogels - exploiting the self- assembly properties of phospholipids. Bobone was able to trap an enzyme using nanometeric particles, while still allowing its activity by the diffusion of substrates and products through the network of the polymer. The innovative nano devices described in this thesis could solve many of the hurdles still hampering the therapeutic application of protein-based drugs.

More books from Springer International Publishing

Cover of the book Education Policy and Power-Sharing in Post-Conflict Societies by Sara Bobone
Cover of the book Prospects for Biological Control of Plant Feeding Mites and Other Harmful Organisms by Sara Bobone
Cover of the book Continuous and Distributed Systems II by Sara Bobone
Cover of the book Inverse Abdominoplasty by Sara Bobone
Cover of the book Space Charge Physics for Particle Accelerators by Sara Bobone
Cover of the book Long Term Evolution in Unlicensed Bands by Sara Bobone
Cover of the book Korea’s Quest for Economic Democratization by Sara Bobone
Cover of the book Pathophysiology of Headaches by Sara Bobone
Cover of the book Advances in Managing Humanitarian Operations by Sara Bobone
Cover of the book Agents and Artificial Intelligence by Sara Bobone
Cover of the book Raymond Smullyan on Self Reference by Sara Bobone
Cover of the book Medical Image Understanding and Analysis by Sara Bobone
Cover of the book Transphobic Hate Crime by Sara Bobone
Cover of the book Safety of Health IT by Sara Bobone
Cover of the book Pattern and Security Requirements by Sara Bobone
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy